Endocrine Abstracts

Introduction: It is known that fasting causes several physiological changes in the endocrine pancreas, such as insulin secretion, pancreatic islet metabolism and beta cells redox state. However, there is still no consensus about the effects of intermittent fasting (IF), a fad diet widespread by the media and adopted by individuals seeking rapid weight loss. In the present study, we sought to study the effects of the IF diet for three months in an animal model.<p class="abs...

Background: Thyroid AUS/FLUS lesions continue to be a grey area regarding the surgery to be carried out. Our aim was to create a predictive malignancy score to help in surgical decision.Methods: Retrospective study of 2981 patients and 3557 thyroid Fine-needle aspirations (FNAs) between January 2012 to December 2014. Ultrasound and cytological findings considered suspicious by the ATA guidelines were analyzed. Malignant group was compared with a control ...

Introduction: Single adenoma is the most frequent cause of Primary hyperparathyroidism (HPT1). Surgical excision has a high success rate, particularly when associated with a fast intraoperative intact parathyroid hormone assay (PTHi).Aim: Evaluate the success rate of primary hyperparathyroidism surgery in our unit.Methods: Descriptive study of the last 33 consecutive HPT1 patients who undertook surgery, 27 of which with PTHi. The P...

Background: The review of the Bethesda System Classification has brought some challenge to the clinical role of category III lesions. Repeating fine-needle aspiration (FNA) is time-consuming, painful, brings additional cost and sometimes does not change the clinical decision. Our aim was to prove if there is true benefit in repeating FNA.Methods: Retrospective review of 4549 thyroid FNAs between January 2012 and June 2015, from which 671 classified as AU...

Background: The clinical attitude to the treatment of Bethesda System Category III lesions has been under controversy. Our aim was to analyse three variables and to establish a possible predictive value for carcinoma in patients with AUS/FLUS nodules.Methods: Retrospective study of 671 thyroid fine-needle aspirations (FNAs) classified as AUS/FLUS between January 2012 and June 2015. Size, sex and age were analysed, using SPSS.Result...

Introduction: Calcium replacement after Thyroid surgery has been changing along times. The aim for this replacement is to avoid hypocalcaemia effects after thyroid surgery but not all the patients seem to need it. Parathyroid hormone (PTH) has a short half-life after its release into the bloodstream, making it a good marker of calcium metabolism in short time after surgery.Method: Prospective study of Endocrine Surgery Multidisciplinary group of one Cent...

Background: Fine-needle aspiration (FNA) is an important test for triaging patients with thyroid nodules and differentiating benign from malignant disease. According to Bethesda System Classification, the rate of AUS/FLUS is between 3–6% of all FNA. The malignancy risk is of 5–15%. TSH levels might be associated to the likelihood of malignancy in thyroid nodules according to some studies. Our aim was to establish a possible correlation between TSH level and malignanc...

Introduction: Although inpatients hyperglycemia is a current uneasiness among the medical community, its prevalence in Portugal in unknown. We aim to identify ‘Stress hyperglycemia’ and ‘New onset diabetes’ cases in inpatients in a district hospital.Methods: We evaluated inpatients from Internal Medicine (IM), General Surgery (GS), Orthopedics and Traumatology (OT) and Stoke Unit (SU) departments, admitted from the emergency departmen...